Chromosomal and gonadal sex drive sex differences in lipids and hepatic gene expression in response to hypercholesterolemia and statin treatment

HIGHLIGHTS

  • who: Carrie B. Wiese from the Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, USA have published the paper: Chromosomal and gonadal sex drive sex differences in lipids and hepatic gene expression in response to hypercholesterolemia and statin treatment, in the Journal: (JOURNAL)
  • what: The authors focused on liver because of its central role in regulating homeostatic lipid levels and as the primary target for statin inhibition of cholesterol synthesis.
  • how: All mouse studies were conducted in accordance with UCLA Institutional Animal Research Committee (IACUC) approval under a . . .

     

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