Chromosome 11q13 amplification correlates with poor response and prognosis to pd-1 blockade in unresectable hepatocellular carcinoma

HIGHLIGHTS

  • who: Kai Yan et al. from the Nanjing Medical University, China have published the Article: Chromosome 11q13 amplification correlates with poor response and prognosis to PD-1 blockade in unresectable hepatocellular carcinoma, in the Journal: (JOURNAL)
  • what: The authors sought to determine the genetic factors that conferred responsiveness to PD-1 blockade in HCC.
  • how: The results showed that the expression of PD-1 and the infiltration of Treg cells was slightly higher in the Amp11q13 group compared to the nonAmp11q13 group which is consistent with the findings of the study .
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