HIGHLIGHTS
- who: Xiaohong Kuang from the Karolinska Institutet (KI), Sweden Wayne State University, United States have published the paper: Chromosome instability and aneuploidy as context-dependent activators or inhibitors of antitumor immunity, in the Journal: (JOURNAL)
- what: The authors provide insights into possible explanations for that disparity and the clinical potential of leveraging CIN/aneuploidy to increase the efficacy of immunotherapy for tumors. numerical chromosomal aberrations, including polyploidy, chromosomal translocation, genome chaos, as well as different types of nonclonal chromosome aberrations (NCCAs) . Heterogeneity in study design and experimental conditions A note of caution should be kept . . .
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