HIGHLIGHTS
SUMMARY
Cilia- and flagella-associated protein 53 (cfap53) played an important role in ciliary rotation, and could regulate the left and right asymmetry of human internal organs (Narasimhan et_al, 2015; Noel et_al, 2016; Gur et_al, 2017). (Schreiber, 2006; Friedman, 2008; Bao et_al, 2011; Li et_al, 2013; Schreiber, 2013). Cells were further lysed and the chromatin was digested, labeled and ligated with biotin (Lieberman-Aiden et_al, 2009). In vertebrates such as humans and zebrafish, mutations in these genes often caused asymmetry in craniofacial tissue and body development (Juriloff et_al, 2006; Marini et_al, 2019), which indicated that . . .
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