Chronic δ9-tetrahydrocannabinol impact on plasticity and differential activation requirement for cb1-dependent long-term depression in ventral tegmental area gaba neurons in adult versus young mice

HIGHLIGHTS

  • who: Isaac Ostlund from the Uniformed Services University, United States have published the paper: Chronic u03949-tetrahydrocannabinol impact on plasticity and differential activation requirement for CB1-dependent long-term depression in ventral tegmental area GABA neurons in adult versus young mice, in the Journal: (JOURNAL)
  • what: The authors show the elimination of LTD after chronic THC in young mice is fully reversible after withdrawal, suggesting THC-induced effects are not permanent.
  • how: For qPCR experiments the authors used VTA samples from mice that were separated into five treatment groups of either young (P15 . . .

     

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