Chronic hyperglycaemia inhibits tricarboxylic acid cycle in rat cardiomyoblasts overexpressing glucose transporter type 4

HIGHLIGHTS

  • who: Bernd Stratmann and colleagues from the Medical Proteome Analysis, Centre for Protein Diagnostics (PRODI), Ruhr-University Bochum, Bochum, Germany have published the article: Chronic Hyperglycaemia Inhibits Tricarboxylic Acid Cycle in Rat Cardiomyoblasts Overexpressing Glucose Transporter Type 4, in the Journal: (JOURNAL)
  • what: To further address this, this study aimed to develop a suitable model for reproducing the onset of DC.
  • how: These results indicated that in hyperglycaemic H9C2KE2 cells further pro-oxidative pathways are activated. To answer the question of whether increased glucose influx affects key metabolic pathways the authors designed the . . .

     

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