Chronic lung diseases are associated with gene expression programs favoring sars-cov-2 entry and severity

HIGHLIGHTS

  • who: Linh T. Bui from the Division Vanderbilt University have published the research work: Chronic lung diseases are associated with gene expression programs favoring SARS-CoV-2 entry and severity, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of May/18,/2021
  • what: Since ACE2 is the best-establishedSARS-CoV-2 entry factor, and AT2 cells accounted for 54.63% of all ACE2 + epithelial_cells, the authors focused on the transcriptional profile of ACE2 + AT2 cells. One limitation of the study is that the authors focus mainly on the peripheral regions of the lungs, and do not . . .

     

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