Chronic n-acetylcysteine treatment prevents amphetamine-induced hyperactivity in heterozygous disc1 mutant mice, a putative prodromal schizophrenia animal model

HIGHLIGHTS

• who: Chuan-Ching Lai and collaborators from the Department of Post-Baccalaureate Veterinary Medicine, Asia University, Taichung, Taiwan have published the Article: Chronic N-Acetylcysteine Treatment Prevents Amphetamine-Induced Hyperactivity in Heterozygous Disc1 Mutant Mice, a Putative Prodromal Schizophrenia Animal Model, in the Journal: (JOURNAL)
• what: This study demonstrated a potent preventive effect of NAC treatment in Disc1 Het on the acute Amph test which mimics the outbreak of psychosis. The neurocognitive deficit is one of the core features of SZ and the treating strategy is still a major research goal in clinical psychiatry .
 



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