Chrysin ameliorates synovitis and brosis of osteoarthritic broblast-like synoviocytes in rats through perk/txnip/ nlrp3 signaling

HIGHLIGHTS

• who: PERK/TXNIP/NLRP and collaborators from the Northwestern Polytechnical University, China have published the research: Chrysin ameliorates synovitis and brosis of osteoarthritic broblast-like synoviocytes in rats through PERK/TXNIP/ NLRP3 signaling, in the Journal: (JOURNAL)
• what: This study shows that CHR can alleviate synovitis and fibrosis in an ACLT-induced animal model and TGF-u03b2-induced cell model. The authors investigated whether CHR reduced synovitis and fibrosis in_vivo and in_vitro. The authors sought to determine how CHR affected KOA synovitis and fibrosis in an ACLT model, as well as in cultured SFs that . . .
  

   

  

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