HIGHLIGHTS
- who: Sarah A. Howles et al. from the University of Oxford, Oxford, United Kingdom have published the research: Cinacalcet corrects hypercalcemia in mice with an inactivating Gα11 mutation Academic Endocrine Unit Radcliffe, in the Journal: JCI Insight. 2017;2(20):e96540. of July/27,/2017
- what: The studies have established a mouse model with a germline loss-offunction Gα11 mutation that is representative for FHH2 in humans and demonstrated that cinacalcet can correct the associated abnormalities of plasma calcium and PTH. Consistent with these findings, the study showed a 10 nM concentration of . . .
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