Circifngr2 enhances proliferation and migration of crc and induces cetuximab resistance by indirectly targeting kras via sponging to mir-30b

HIGHLIGHTS

• who: Qi Zhang from the DepartmentMedical University, Guangzhou, Guangdong, China have published the research: CircIFNGR2 enhances proliferation and migration of CRC and induces cetuximab resistance by indirectly targeting KRAS via sponging to MiR-30b, in the Journal: (JOURNAL) of 27/05/2022
• what: By and large, the research explored the molecular mechanism of cetuximab resistance in WT-KRAS and MUT-KRAS CRC patients.
• how: Interestingly results showed that the protein expression level of p-ERK and p-AKT was upregulated in the circIFNGR2 overexpressed group of WT-KRAS cells while the protein expression . . .
  

   

  

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