Circrna: a new class of targets for gastric cancer drug resistance therapy

HIGHLIGHTS

  • who: March et al. from the Innsbruck Medical University, Austria have published the paper: CircRNA: A new class of targets for gastric cancer drug resistance therapy, in the Journal: (JOURNAL)
  • what: The main reason for the high GC mortality rate is likely due to its diagnosis in the advanced or metastatic stage . Research has shown that autophagy dysregulation may be one of the main reasons for drug resistance in cancer, in which circCPM participates .
  • how: The data indicated that circRACGAP1 regulated apatinib-induced autophagy by targeting miR-3657 and ATG7.
  • future . . .

     

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