Circrna-creit inhibits stress granule assembly and overcomes doxorubicin resistance in tnbc by destabilizing pkr

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  • who: Xiaolong Wang from the Department of Breast Surgery, General Surgery, Qilu Hospital of Shandong University, No, Wenhua Xi Road, Jinan, Shandong, China have published the article: CircRNA-CREIT inhibits stress granule assembly and overcomes doxorubicin resistance in TNBC by destabilizing PKR, in the Journal: (JOURNAL)
  • what: The authors demonstrated that circRNA-CREIT was aberrantly downregulated in doxorubicin resistant triple-negative breast cancer (TNBC) cells and associated with a poor prognosis. The study demonstrated that targeting circRNA-CREIT and SGs could serve as promising therapeutic strategies against TNBC chemoresistance. The study was approved by the . . .

     

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