Circrna432 enhances the coelomocyte phagocytosis via regulating the mir-2008-elmo1 axis in vibrio splendidus-challenged apostichopus japonicus

HIGHLIGHTS

• who: Xianmu Fu from the Ningbo University, Ningbo, PR. China. have published the Article: circRNA432 enhances the coelomocyte phagocytosis via regulating the miR-2008-ELMO1 axis in Vibrio splendidus-challenged Apostichopus japonicus, in the Journal: (JOURNAL) of 20/01/2023
• what: The authors report a circ432-miR-2008-AjELMO1 axis interaction network that mediates V. splendidus-induced coelomocytes phagocytosis in sea cucumbers (Fig 8). miR-2008 can reduce the abundance of AjELMO1 and inhibit AjELMO1mediated phagocytosis of coelomocytes which may help V. splendidus to evade the host antimicrobial response. The sea cucumbers A. japonicus used . . .
  

   

  

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