Circular rna circtmem241 drives group iii innate lymphoid cell differentiation via initiation of elk3 transcription

HIGHLIGHTS

  • who: Nian Liu from the (UNIVERSITY) have published the Article: Circular RNA circTmem241 drives group III innate lymphoid cell differentiation via initiation of Elk3 transcription, in the Journal: (JOURNAL) of 17/03/2022
  • what: The authors show that circTmem241 is highly expressed in ILC progenitors and regulates ILC3 specification from the ILCP stage. The authors showed that circTmem241 directly interacts with Nono to recruit Ash1l onto Elk3 promoter in ILCPs.
  • how: CircTmem241 regulates ILC3 commitment in an intrinsic manner To further determine whether the role of circTmem241 in ILC3 commitment is intrinsic or . . .

     

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