Circulating insulin-like growth factors and risks of overall, aggressive and early-onset prostate cancer: a collaborative analysis of 20 prospective studies and mendelian randomization analysis

HIGHLIGHTS

  • who: Key Messages and collaborators from the Unit, Nuffield Department Population Health, Oxford, Oxford, UK have published the Article: Circulating insulin-like growth factors and risks of overall, aggressive and early-onset prostate cancer: a collaborative analysis of 20 prospective studies and Mendelian randomization analysis, in the Journal: (JOURNAL)
  • what: The authors aimed to investigate the associations of IGF-I, IGF-II, IGFBP-1, IGFBP-2 and IGFBP-3 concentrations with overall, aggressive and early-onset prostate cancer. For the first time the authors show evidence that IGF-I is important for aggressive, clinically relevant . . .

     

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