Circulating metabolites and depression: a bidirectional mendelian randomization

HIGHLIGHTS

  • who: Yankai Dong from the University of Mississippi Medical Center, United States have published the research work: Circulating metabolites and depression: a bidirectional Mendelian randomization, in the Journal: (JOURNAL)
  • what: The study shows that isoleucine is a risk factor for depression, and the risk of depression increases with isoleucine exposure.
  • how: In this study MR was used to explore and clarify the causal effect of circular metabolites on depression and tested whether the effect is bidirectional. The genomic location used in the research is human genome construction. The result showed that glutamine (OR . . .

     

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