Circulating tumor dna reveals complex biological features with clinical relevance in metastatic breast cancer

HIGHLIGHTS

• who: Aleix Prat from the (UNIVERSITY) have published the research: Circulating tumor DNA reveals complex biological features with clinical relevance in metastatic breast cancer, in the Journal: (JOURNAL) of 14/02/2023
• what: The authors demonstrate that machine_learning multi-gene signatures, obtained from ctDNA, identify complex biological features, including measures of tumor proliferation and estrogen receptor signaling, similar to what is accomplished using direct tumor tissue DNA or RNA profiling. The work demonstrates that complex tumor phenotypic traits can be identified in ctDNA and might be clinically relevant in advanced breast cancer. Of note, all . . .
  

   

  

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