SUMMARY
Cis P-tau was detected in early- (e-PE) and late (l-PE)-onset PE placental tissues (e-PE, n=7; l-PE, n=10), but not in an equal number of gestational agematched controls, whereas trans P-tau was mainly present in control placenta (Fig 1a, and Supplementary Figs 1a-f, 2a, b). In contrast, cis P-tau, but not trans P-tau, was present in the insoluble form in e-PE placenta (Fig 1b), suggesting the aggregated nature of cis P-tau. A strong cis P-tau signal mainly localized to the trophoblast layer in . . .
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