Cisplatin promotes the ef fi cacy of immune checkpoint inhibitor therapy by inducing ferroptosis and activating neutrophils

HIGHLIGHTS

• who: Activating and collaborators from the Department of Oncology, Sun Yat-Sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China, Phase I Clinical Trial have published the paper: Cisplatin Promotes the Ef fi cacy of Immune Checkpoint Inhibitor Therapy by Inducing Ferroptosis and Activating Neutrophils, in the Journal: (JOURNAL)
• how: The results showed that cisplatin induced A549 cell death in a dosedependent manner and about 50% of cell death could be rescued by ferrostatin-1 as a ferroptosis inhibitor . The above results indicated that neutrophils play an important role in anti-tumor immune_response. The results . . .
  

   

  

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