Clinical and experimental immunology 1-10 pepitem modulates leukocyte trafficking to reduce obesity-induced inflammation

HIGHLIGHTS

  • who: Advance access, publication and March, from the Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK have published the research: Clinical and Experimental Immunology 1-10 PEPITEM modulates leukocyte trafficking to reduce obesity-induced inflammation, in the Journal: (JOURNAL) of 14/Nov/2022
  • what: The authors investigate the impact of the immunopeptide PEPITEM on pancreas homeostasis and leukocyte trafficking in mice on highfed obesogenic diet (HFD). The authors report for the first time that PEPITEM treatment, either prophylactically or therapeutically, limits T-cell trafficking (CD4+ T-cells, CD3+KLRG1+ senescent T-cells) to . . .

     

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