HIGHLIGHTS
- who: Treg and collaborators from the Department of General Surgery, Medical University of Vienna, Vienna, Austria have published the research: Clinical and Experimental Immunology XX 1-16, in the Journal: (JOURNAL)
SUMMARY
Heterogeneity of regulatory T_cells Tregs comprise about 5-10% of circulating CD4 + T_cells and are characterized by the constitutive and high expression of CD25 and FOXP3. While FOXP3 expression in mice is specific for Tregs, in humans it has been shown that CD4 + CD25-effector T_cells (Teff) are capable of transiently expressing the transcription factor. While thymus derived Tregs mainly recognize . . .
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