HIGHLIGHTS
- who: Abbreviations CMC chronic mucocutaneous et al. from the InstitutUniversity College London, London, UK have published the research: Clinical and Experimental Immunology XX 1-4 Letter to the Editor Letter to the Editor, in the Journal: (JOURNAL)
SUMMARY
Most immunology laboratories that offer validation assays for STAT1 VUS rely on comparing pSTAT1 levels between a potential index case and one or a group of healthy controls. Levels of pSTAT1 at baseline and upregulation after cytokine stimulation vary considerably in the healthy population and overlap with levels observed in STAT1 GOF patients. The authors . . .
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