Clinical and preclinical evidence for roles of soluble epoxide hydrolase in osteoarthritis knee pain

HIGHLIGHTS

  • who: Arthritis Rheumatology from the (UNIVERSITY) have published the research: Clinical and Preclinical Evidence for Roles of Soluble Epoxide Hydrolase in Osteoarthritis Knee Pain, in the Journal: (JOURNAL)
  • what: The authors report for the first time that SNPs of the soluble EH gene EPHX2 are associated with 3 different measures of knee pain in subjects with OA, substantially adding to the previous evidence that plasma levels of some DHETs are associated with OA joint pathology and progression . The authors provide substantive new clinical and preclinical evidence that soluble EH is an important mediator of OA . . .

     

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