HIGHLIGHTS
SUMMARY
Among them, eosinophil and eosinophil-associated signaling pathways play a key role in antitumor immunity and induction of epithelial mesenchymal transition (De Palma et_al, 2017; Korbecki et_al, 2020). Eosinophils readily respond to a variety of stimuli by synthesizing and secreting a large number of molecules, including unique granulin proteins that may kill tumor cells (Grisaru-Tal et_al, 2020). Studies have shown that some cytokines (IL-4, IL-5) can increase the antitumor activity of eosinophils (Furbert-Harris et_al, 2003). Cancer immunotherapy is not limited to understanding the relationship between cancer and the immune system . . .
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