Clinical evaluation based on a new approach to improve the accuracy of 4-hydroxycholesterol measurement as a biomarker of cyp3a4 activity

HIGHLIGHTS

  • who: Yuki Taya and collaborators from the Laboratory of Food Function Analysis, Graduate School of Agricultural Science, Tohoku University, Sendai, Miyagi, Japan have published the paper: Clinical Evaluation Based on a New Approach to Improve the Accuracy of 4-Hydroxycholesterol Measurement as a Biomarker of CYP3A4 Activity, in the Journal: Molecules 2023, 1576 of 25/01/2023
  • what: This study examines (4u03b2-HC) which is considered to be a potential marker for the CYP3A4 induction of new chemical entities (NCEs) in drug development. The authors examined the effects of these manipulations on the measurement of . . .

     

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