Clinical features and biomarkers of semantic variant primary progressive aphasia with mapt mutation

HIGHLIGHTS

  • who: Jing Xu from the Medical University General Hospital, Anshan Road, Heing District, Tianjin, China have published the Article: Clinical features and biomarkers of semantic variant primary progressive aphasia with MAPT mutation, in the Journal: (JOURNAL)
  • what: The authors described a Chinese family with svPPA that was caused by the MAPT P301L mutation. This study provides an ideal model for inferring the underlying pathology and pathophysiological processes in svPPA due to tauopathies. svPPA is exceptional among FTLD phenotypes in the sense that it is typically sporadic, with the least likelihood of a genetic cause ; only . . .

     

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