Clinical medicine aerobic exercise elicits clinical adaptations in myotonic dystrophy type patients independently of pathophysiological changes

HIGHLIGHTS

  • who: Andrew I. Mikhail and collaborators from the DepartmentMcMaster University Medical Center, Hamilton, Ontario, Canada have published the Article: CLINICAL MEDICINE Aerobic exercise elicits clinical adaptations in myotonic dystrophy type patients independently of pathophysiological changes, in the Journal: (JOURNAL)
  • what: The authors provide evidence for the involvement of snoRNAs and other noncoding RNAs in DM1 pathophysiology. 2 Herein, the authors show that 12 weeks of moderate intensity cycling elicits myriad benefits in DM1 patients without altering the molecular pathophysiology or transcriptomic signature relating to RNA toxicity. The study demonstrates the efficacy of moderate intensity cycling . . .

     

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