Clinical testing for mismatch repair in neoplasms using multiple laboratory methods

HIGHLIGHTS

• who: Richard K. Yang and collaborators from the Department Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA have published the article: Clinical Testing for Mismatch Repair in Neoplasms Using Multiple Laboratory Methods, in the Journal: (JOURNAL) of 11/07/2022
• what: For most neoplasms, IHC and PCR-based MSI testing results are concordant.

SUMMARY

As discussed above, the downstream effect of mismatch repair deficiency is microsatellite instability as well as subsequent genetic mutations that can drive neoplasia, whereas the upstream cause of MSI-H is mutations in . . .

 



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