Clinical usefulness of presepsin and monocyte distribution width (mdw) kinetic for predicting mortality in critically ill patients in intensive care unit

HIGHLIGHTS

• What: The authors explored the accuracy of two new sepsis biomarkers, MDW and PSP, compared to traditional ones, C-reactive protein (CRP) and Procalcitonin (PCT), to predict ICU mortality by analyzing their kinetic at different time points during ICU stay. Based on the specified decisional threshold and subsequent analysis, the investigation has identified the potential existence of a categorical biomarker integrating both static and dynamic measurements of PSP levels. With the awareness that the ideal sepsis biomarker does not exist, the research is focused on identifying reliable biomarkers to assist Clinicians in the appropriate patient management, from . . .
  

   

  

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