HIGHLIGHTS
SUMMARY
In the list of "newer" antidepressants, Bupropion has been described as a potential option for the treatment of depressive symptoms in PD. Despite these theoretical properties, Bupropion efficacy on depressive symptoms in PD has been reported only in limited clinical investigations. Considering this background, the authors primarily sought to review the current knowledge on the effectiveness and safety of Bupropion in patients with PD and comorbid depressive symptoms. The research question consisted of investigating the therapeutical uses of Bupropion in patients with a diagnosis of PD (or parkinsonism) who manifested depressive symptoms or other . . .
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