Clinicopathological and prognostic significance of swi/snf complex subunits in undifferentiated gastric carcinoma

HIGHLIGHTS

  • who: Zhenkun Zhang from the Department of Pathology, Weihai Municipal Hospital, Shandong University, Weihai, Shandong, China have published the paper: Clinicopathological and prognostic significance of SWI/SNF complex subunits in undifferentiated gastric carcinoma, in the Journal: (JOURNAL)
  • what: The authors defined SRY-box transcription factor 2 (SOX2) or Spalt-like transcription factor 4 (SALL4) positivity as the CSC phenotype , which is characterized by high self-renewal capacity, strong invasiveness, and resistance to chemotherapy and radiotherapy . The authors focused mainly on the correlation of the SWI/SNF complex with CSC phenotype and prognosis.
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