Clk1/clk2-driven signalling at the leishmania kinetochore is captured by spatially referenced proximity phosphoproteomics

HIGHLIGHTS

• who: Vincent Geoghegan from the Department University of York, Wentworth Way, Heslington, York , DD, UK have published the paper: CLK1/CLK2-driven signalling at the Leishmania kinetochore is captured by spatially referenced proximity phosphoproteomics, in the Journal: (JOURNAL) of 10/08/2022
• what: The authors show here that CLK1/CLK2 inhibition by AB1 does not block spindle formation in Leishmania which corroborates the findings in brucei when CLK1 was chemically inhibited or knocked down7 25.
• how: To gain insight into the kinetochore and kinetochore protein kinases in Leishmania the authors developed a high . . .
  

   

  

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