Clonal hematopoiesis of indeterminate potential, dna methylation, and risk for coronary artery disease

HIGHLIGHTS

• who: M d Mesbah Uddin from the Study cohorts The Cardiovascular Health Study (CHS) is a population-based cohort for studying the risk factors for coronary heart disease and stroke in people u2265, years of age Our discovery sample consisted of , CHS participants who had both CHIP and DNAm data available. DNAm was measured from blood samples taken from these participants in years , and , (N=405), year , (N=171), or year , only (N=6). CHIP calls were based on whole-genome sequences (WGS) of blood samples, the majority of which were taken , years prior (year, N=192 . . .
  

   

  

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