Cloning and characterization of the promoter region of the rat epidermal growth factor receptor gene and its transcriptional regulation by nerve growth factor in pc12 cells*

HIGHLIGHTS

  • who: Xu-Wen Liu from the (UNIVERSITY) have published the Article: Cloning and Characterization of the Promoter Region of the Rat Epidermal Growth Factor Receptor Gene and Its Transcriptional Regulation by Nerve Growth Factor in PC12 Cells*, in the Journal: (JOURNAL) of April/21,/1999

SUMMARY

    The NGFinduced down-regulation of the EGFR is under transcriptional_control. To elucidate the molecular mechanism of this down-regulation the authors have cloned a 2.7kilobase sequence from the promoter region of the rat EGFR from a rat P1 library. The results demonstrate that TCC repeat sequences . . .

     

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