Close-up of the immunogenic α1,3-galactose epitope as defined by a monoclonal chimeric immunoglobulin e and human serum using saturation transfer difference (std) nmr

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  • who: Melanie Plum from the (UNIVERSITY) have published the Article: Close-up of the Immunogenic α1,3-Galactose Epitope as Defined by a Monoclonal Chimeric Immunoglobulin E and Human Serum Using Saturation Transfer Difference (STD) NMR, in the Journal: (JOURNAL) of December/16,/2011
  • what: The authors aimed for a direct monitoring of the interplay of anti-Gal antibodies with the cognate antigen on a molecular level and comparability of the monoclonal IgE with polyclonal serum antibodies. The authors report the construction of chimeric immunoglobulins on the basis of an ␣-Gal-specific antibody fragDECEMBER 16 . . .

     

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