Clostridium perfringens epsilon toxin binds to and kills primary human lymphocytes

HIGHLIGHTS

• who: Samantha V. Shetty and collaborators from the Harold and Margaret Milliken Hatch Laboratory of Neuro-Endocrinology Rockefeller University, New York, NY, USA have published the paper: Clostridium perfringens Epsilon Toxin Binds to and Kills Primary Human Lymphocytes, in the Journal: Toxins 2023, 15, 423. of 31/03/2023
• what: The authors demonstrate that preferentially binds to and kills human lymphocytes expressing increased levels of the myelin and lymphocyte protein Using flow cytometry binding was determined to be time and dose dependent and was highest for CD4+ cells followed by CD8+ and then CD19+ cells . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.