Clozapine long-term treatment might reduce epigenetic age through hypomethylation of longevity regulatory pathways genes

HIGHLIGHTS

• who: Humberto Nicolini and Nancy Monroy-Jaramillo from the University of Cagliari, Italy have published the research: Clozapine Long-Term Treatment Might Reduce Epigenetic Age Through Hypomethylation of Longevity Regulatory Pathways Genes, in the Journal: (JOURNAL)
• what: This work aimed to evaluate epigenetic age and DNA methylome differences between patients treated with CLZ and psychiatric patients without psychopharmacological treatment. The authors report the first differential methylation analysis in a Latin American population between CLZ-treated patients with refractory psychosis and drug-naive patients with psychiatric disorders. The authors only evaluated DNA methylome, future longitudinal studies . . .
  

   

  

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