Clpp depletion causes diplotene arrest; underlying testis mitochondrial dysfunction occurs with accumulation of perrault proteins eral1, peo1, and hars2

HIGHLIGHTS

  • who: Jana Key et al. from the Faculty, Goethe University, Frankfurt am Main, Germany have published the research: CLPP Depletion Causes Diplotene Arrest; Underlying Testis Mitochondrial Dysfunction Occurs with Accumulation of Perrault Proteins ERAL1, PEO1, and HARS2, in the Journal: Cells 2023, 12, x FOR PEER REVIEW of 22/Nov/2022
  • what: The authors propose that the loss of CLPP leads to the extrusion of nucleotide-binding to cytosol and nucleus affecting late meiotic prophase progression and causing cell death prior to M-phase entry. In this survey, the authors aim to define the cytological . . .

     

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