Cmv-independent increase in cd27−cd28+ cd8+ emra t cells is inversely related to mortality in octogenarians

HIGHLIGHTS

• who: Carmen Martin-Ruiz from the Animals, procedures and senolytic treatment C BL/, mice were analyzed at either , weeks (, months) or , weeks (, months) of ageMice were purchased from Charles River (Charles River Laboratories International, UK). The project was approved by the Faculty of Medical Sciences Ethical Review Committee, Newcastle University (project license no., ). At ~, months of age, mice were randomly assigned to a treatment group. , (navitoclax) or vehicle alone was administered to mice by gavage at , mg/kg body weight per day (mg/ kg/d) for , day per cycle for two cycles with a, week interval between . . .
  

   

  

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