HIGHLIGHTS
- who: Megan Lo from the University of California, San Francisco, CA, USA have published the research: CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- what: The authors demonstrate the developmental consequences of Cnpy4 knockout in mice and report the unique role that CNPY4 plays in the regulation of HH signaling. Due to the high penetrance of the limb phenotype and | https://doi.org/10.1038/s41467-022-30186-x a Preaxial polydactyly (6 digits) Posteriorization (5 digits) Wild type (5 digits) Control Cnpy4 Sox9 C np . . .
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