Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence

HIGHLIGHTS

• who: Xiao-Chuan Li from the Department of Orthopaedic Surgery, Gaozhou People’s Hospital, Guangdong, China have published the article: Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence, in the Journal: (JOURNAL)
• what: The aim of this study was to investigate the effects of NC-rich NP explant coculture on cell morphological features, proliferation, senescence, and extracellular gene/protein expression in NPMSCs.
• how: In this study tumor necrosis factor (TNF)-α was used to mimic the inflammatory environment of IDD. Based on . . .
  

   

  

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