Co-formulation of amphiphilic cationic and anionic cyclodextrins forming nanoparticles for sirna delivery in the treatment of acute myeloid leukaemia

HIGHLIGHTS

  • who: Ayse Kont et al. from the School have published the research work: Co-Formulation of Amphiphilic Cationic and Anionic Cyclodextrins Forming Nanoparticles for siRNA Delivery in the Treatment of Acute Myeloid Leukaemia, in the Journal: (JOURNAL)
  • what: The aim of this study was to develop a novel delivery system with reduced charge density by co-formulating amphiphilic cationic CDs with negatively charged amphiphilic CDs. The authors are aiming to simulate this positive effect with the co-formulation of an anionic amphiphilic CD.
  • how: Pre-clinical results showed that KAT2a knockdown at a . . .

     

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