Co lin activation in pancreatic acinar cells plays a pivotal convergent role for mediating cck-stimulated enzyme secretion and growth

HIGHLIGHTS

  • who: April et al. from the University of California, Los Angeles, United States have published the Article: Co lin activation in pancreatic acinar cells plays a pivotal convergent role for mediating CCK-stimulated enzyme secretion and growth, in the Journal: (JOURNAL)
  • what: The study has one potential major weakness in the exploration of the role of LIMK/SSH1 in cofilin activation and the role of cofilin in pancreatic acinar secretion or growth. The authors demonstrate that cofilin activation (i.e., dephosphorylation) is mediated by activation of PKC/PKD, Src, PAK4, JNK, ROCK and activation of . . .

     

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