Co-stimulatory receptor signaling in car-t cells

HIGHLIGHTS

  • who: Mackenzie M. Honikel and Scott H. Olejniczak from the Immunology Department, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA have published the Article: Co-Stimulatory Receptor Signaling in CAR-T Cells, in the Journal: Biomolecules 2022, 12, 1303. of 15/09/2022
  • what: The authors provide an overview of CAR-T cell co-stimulation by the prototypical receptors and discuss current and emerging strategies to modulate co-stimulatory signals to enhance CAR-T cell function. The work of multiple different groups over the course of the past several years has focused precisely on the . . .

     

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