Co-targeting bcl-xl and mcl-1 with dt2216 and azd8055 synergistically inhibit small-cell lung cancer growth without causing on-target toxicities in mice

HIGHLIGHTS

• who: Sajid Khan from the Chemical compounds , was synthesized in DrGuangrong Zheng`s laboratory (University of Florida, Gainesville, FL) according to the previously described protocol [16]. , (Cat. No. HY-10422) and everolimus (Cat. No. HY-10218) were purchased from MedChemExpress (Monmouth Junction, NJ). , (Cat. No., ), (Cat. No., ), (Cat. No., ), and , (Cat. No., ) were purchased from SelleckChem (Houston, TX). have published the research: Co-targeting BCL-XL and MCL-1 with DT2216 and AZD8055 synergistically inhibit small-cell lung cancer growth without causing on-target toxicities in mice, in the Journal: (JOURNAL) of 30/09/2022
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