Co-targeting triple-negative breast cancer cells and endothelial cells by metronomic chemotherapy inhibits cell regrowth and migration via downregulation of the fak/vegfr2/vegf axis and autophagy/apoptosis activation

HIGHLIGHTS

• who: Arianna Scagliotti and colleagues from the University College Dublin, Ireland Sciences, Iran have published the research: Co-targeting triple-negative breast cancer cells and endothelial cells by metronomic chemotherapy inhibits cell regrowth and migration via downregulation of the FAK/VEGFR2/VEGF axis and autophagy/apoptosis activation, in the Journal: (JOURNAL)
• what: The authors demonstrate that 5-FU and VNR given mCHT as single agents, or in combination, strongly reduce the survival of ECs, as the authors previously reported for TNBC cells . Given the reduction in cell survival recorded by MTT and clonogenic assays the . . .
  

   

  

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