Cocktail of isobavachalcone and curcumin enhance eradication of staphylococcus aureus biofilm from orthopedic implants by gentamicin and alleviate inflammatory osteolysis

HIGHLIGHTS

  • who: ufeffChunufeff ufeffLiuufeff and ufeffXuenongufeff ufeffZouufeff from the Yat-sen University, China have published the article: Cocktail of isobavachalcone and curcumin enhance eradication of ufeffStaphylococcus aureusufeff biofilm from orthopedic implants by gentamicin and alleviate inflammatory osteolysis, in the Journal: (JOURNAL)
  • what: As the authors show in_vitro and in_vivo experiments, using gentamicin alone was difficult to suppress MRSA proliferation and local infection progression, but once added both ISB and CRM, the inhibitory and bactericidal effect of gentamicin against MRSA enhanced significantly.
  • how: After the residual biofilm was quantified the synergistic effect could not be . . .

     

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