Codelivery of doxorubicin/pi3k inhibitor nanomicelle linked with phenylboronic acid for enhanced cytotoxicity to pancreatic cancer

HIGHLIGHTS

  • who: Pancreatic Cancer and colleagues from the Department of Laboratory Medicine, The First Affiliated Hospital of Hunan Normal University, Changsha, Hunan, China have published the research work: Codelivery of Doxorubicin/PI3K Inhibitor Nanomicelle Linked with Phenylboronic Acid for Enhanced Cytotoxicity to Pancreatic Cancer, in the Journal: Journal of Nanomaterials 100 of 23/06/2022
  • how: The authors used phenylboronic acid and polyethylene glycol as materials of nanomicelles loaded with the PI3K/mTORC1 dual inhibitor PF04691502 (PF) to inhibit the resistance and metastasis of and increase the sensitivity of doxorubicin (DOX). The results showed that the . . .

     

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