Coenzyme a binding sites induce proximal acylation across protein families

HIGHLIGHTS

  • who: Chris Carrico from the Buck Institute have published the paper: Coenzyme A binding sites induce proximal acylation across protein families, in the Journal: Scientific Reports Scientific Reports of 28/07/2022
  • what: Most cellular acylation sites are found in the mitochondria, and the authors focused this investigation on mitochondrial proteins, using acylomic datasets from mitochondria extracts.
  • how: Western blotting results showed that succinylation levels induced by succinyl-CoA incubation were increased in a time-dependent manner in both proteins (Fig 5c). Similarly | Vol.(1234567890) 135029 | MS analysis results showed that acetylation at . . .

     

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